Preheat your oven to 350°F (180°C), or 160°C if you have a fan oven. Line a baking sheet with aluminum foil or parchment paper for an easier cleanup later.
In a large bowl, combine the chicken thighs with olive oil, salt, garlic powder, onion powder, paprika, cayenne, and black pepper. Toss everything together well to ensure the chicken is evenly coated with the seasoning.
Place the chicken thighs on the prepared baking sheet in a single layer, making sure they're not touching.
Bake in the preheated oven for 15-20 minutes, or until the chicken reaches an internal temperature of 165°F (74°C) when checked with a meat thermometer. If desired place under the broiler for a couple of minutes.
Remove the chicken from the oven and let it rest for about 5 minutes. This helps the juices redistribute and keeps your chicken moist. Serve the baked chicken thighs with your choice of sides, like mashed potatoes, rice, pasta, salad, or steamed veggies.